"We loved coming back to this quiet hotel every day after exploring the sights of magnificent Rome. We were so well looked after by all the reception staff. The family room was perfect for our family o..."
Guests love it hereGuests give this property a top rating
Top-tier experienceA high end property in this area
Book with confidenceWe partner with the top travel sites so you know you're getting a great deal on the perfect rental
About this hotel
Just 220 yards from St Peter’s Basilica, Sant’Anna Hotel is a 17th-century building offering elegant rooms and interiors in central Rome. Wi-Fi is free and a varied continental breakfast is available.
Amenities
Airport transportation available
Shuttle available
Concierge services
Free WiFi/internet
Air conditioning
Non-smoking
Heating
WiFi/Internet
Garden
Family friendly
Safe
Accessible by lift
Key access
Housekeeping available
Fire alarm
Fire extinguisher
Cleaning products
Map of Rome
Available Rooms
Ratings and reviews
9.1 / 10
Outstanding(683 Ratings)
100% verified reviews
10 / 10Outstanding·Oct 2026
We loved coming back to this quiet hotel every day after exploring the sights of magnificent Rome. We were so well looked after by all the reception staff. The family room was perfect for our family of four. We really enjoyed the breakfast every morning too. Thanks for taking such lonely care of us.
Nothing.
10 / 10Outstanding·Oct 2026
This is a great hotel right in the centre of Vatican city. Staff were so helpful and accommodating. I would definitely go back again. Rooms were immaculate and a great size.
Nothing
10 / 10Outstanding·Oct 2026
Fantastic location, beautiful, very clean.
The pillows good be softer.
5 / 10·Aug 2026
The LOCATION- right near the St Peter's Basilica- so near the Vatican.
Our stay was okay overall, but the location was definitely the highlight. It was amazing—however, I actually found another hotel on the same street that had a much better atmosphere and energy.
The rooms are extremely close to each other, and the doors are very noisy because they require a lot of force to open and close. The hotel also uses large traditional keys for the rooms and a card system for the lights, which felt a bit outdated.
Unfortunately, our experience with the noise complaints was very disappointing. My teenagers told me that while they were in the room, someone knocked very loudly on the door, and of course they did not open it. About 10 minutes later, after we arrived, we were simply talking normally when someone knocked loudly on the door again. We did not open it, and the whole situation started to feel uncomfortable—almost like something you would see in a cheap hotel movie. Later, there was another small knock, and we still did not open the door. Shortly after, the front desk called to inform us that they had received two noise complaints. I explained firmly that we were already in bed at that point.
I was very disappointed with how the situation was handled. It felt like the hotel prioritized other guests’ complaints without considering our side of the story, perhaps because we were traveling with teenagers. If the hotel is intended for guests who prefer complete silence, no teens allowed, they should clearly state that. They should also be transparent about how close the rooms are to each other, since normal conversations can easily be heard.
Because of this experience, I would not stay here again or recommend this hotel to others. The breakfast also lacked variety, and considering the price we paid, I expected much more—similar to the quality and selection I experienced at hotels in Venice, Florence, or even Naples.
$$$$
Top rated by guests
9.1Outstanding
(683 Ratings)
"We loved coming back to this quiet hotel every day after exploring the sights of magnificent Rome. We were so well looked after by all the reception staff. The family room was perfect for our family o..."
Guests love it hereGuests give this property a top rating
Top-tier experienceA high end property in this area
Book with confidenceWe partner with the top travel sites so you know you're getting a great deal on the perfect rental
Map of Rome
Available Rooms
About this hotel
Just 220 yards from St Peter’s Basilica, Sant’Anna Hotel is a 17th-century building offering elegant rooms and interiors in central Rome. Wi-Fi is free and a varied continental breakfast is available.
Amenities
Airport transportation available
Shuttle available
Concierge services
Free WiFi/internet
Air conditioning
Non-smoking
Heating
WiFi/Internet
Garden
Family friendly
Safe
Accessible by lift
Key access
Housekeeping available
Fire alarm
Fire extinguisher
Cleaning products
FAQs
Is parking included with this hotel?
Parking is not specified as an available amenity at Hotel S. Anna. For more information, we encourage you to contact the property about where to park.
Is there a pool at this hotel?
We didn’t find pool listed as an amenity for this hotel. It may be worth double checking if a pool is important for your stay.
Is Hotel S. Anna pet friendly?
Unfortunately, this hotel is not pet-friendly. Try searching again and filter for "Pets Allowed"
What amenities are available at Hotel S. Anna?
We found 17 amenities for this rental. This includes airport transportation available, shuttle available, concierge services, free wifi/internet, and air conditioning.
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