Hotel in Rome
4-Star Hotel
Reasons to book
Guests love it hereGuests give this property a top rating
Top-tier experienceA high end property in this area
Book with confidenceWe partner with the top travel sites so you know you're getting a great deal on the perfect rental
About this hotel
Along with a restaurant, this smoke-free hotel has a fitness center and a bar/lounge. WiFi in public areas is free. Additionally, a snack bar/deli, self parking, and conference space are onsite.
Twentyone Hotel offers 96 accommodations with minibars and safes. Each accommodation is individually decorated. Beds feature premium bedding. Flat-screen televisions come with premium satellite channels and pay movies. Bathrooms include showers, bidets, complimentary toiletries, and hair dryers.
Recreational amenities at the hotel include a fitness center.
Twentyone Hotel offers 96 accommodations with minibars and safes. Each accommodation is individually decorated. Beds feature premium bedding. Flat-screen televisions come with premium satellite channels and pay movies. Bathrooms include showers, bidets, complimentary toiletries, and hair dryers.
This Rome hotel provides complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones. Housekeeping is offered daily and irons/ironing boards can be requested.
Recreational amenities at the hotel include a fitness center.
The recreational activities listed below are available either on site or nearby; fees may apply.
Amenities
Non-smoking
Map of Rome
Available Rooms
Ratings and reviews
8 / 10Excellent·Jul 2026
Great based hotel but standard double, lighting is poor, wardrobe squeezed in to an angle making it difficult to hang clothes and no drawer space ??
8 / 10Excellent·Jul 2026
Everything was just what we needed, the location was amazing, we walked to everything. The staff spoke English fluently so that was a nice break for my tired brain. The breakfast had so many choices it was hard to pick and the breakfast room had a lovely view over Rome. I only deducted a star because the room was warm even with the AC on full and the toilet kept running it would have to be re-flushed to make it stop (not the end of the world, but annoying). The room was smaller than some but elegant and had everything we needed.
10 / 10Outstanding·May 2026
Great location. Clean rooms and property. Excellent service from staff. Was not my 1st time staying here. It won't be my last. Hotel TwentyOne is my favorite hotel in Rome
5 / 10·Jun 2026
Perfect vacation for our family!
$$$$
Top rated by guests
8.2Excellent
(1,016 Ratings)
"Great location. Clean rooms and property. Excellent service from staff. Was not my 1st time staying here. It won't be my last. Hotel TwentyOne is my favorite hotel in Rome"
VincentDon't miss out! Price and availability may change
